A scientific visualisation of a myelinated nerve fibre, the myelin sheath damaged in multiple sclerosis

Multiple sclerosis · RRMS · SPMS · PPMS — all stages

Calming the immune attack in MS

MS damages the myelin that protects your nerves, disrupting movement, sensation and energy. Our treatment targets the biology driving it — calming the immune attack and supporting repair — to stabilise function, ease relapses and help you keep your independence. Every plan is built around your subtype and stage.

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A scientific visualisation of a single nerve axon sheathed in segmented myelin

What MS is, in plain terms.

MS is an autoimmune disease of the central nervous system. The immune system attacks the myelin sheath that insulates your nerve fibres, so signals between the brain, spinal cord and body are slowed or blocked. Relapses, fatigue, weakness and problems with balance, sensation and vision follow. Disease-modifying drugs suppress the immune attack; our treatment works on both sides — calming that attack and supporting the conditions for myelin to repair.

RRMS ~85% of first diagnoses
SPMS gradual decline after RRMS
PPMS ~10–15%, progressive from onset
CIS a first demyelinating episode

What the treatment works to protect.

We do not promise a cure. What we work for is to stabilise your neurology and improve daily life — easing relapses and holding on to the functions MS disrupts first, so more of each day stays in your hands.

Mobility & balance Walking stability, balance and lower-limb strength, kept for longer.
Strength & coordination Muscle strength and fine motor control in the hands.
Cognition Concentration, memory and processing speed.
Sensation & bladder Sensory symptoms, bladder control and optic function.
Energy & independence Reducing fatigue and staying independent in daily tasks.

A 3D scientific visualisation of an oligodendrocyte re-wrapping a nerve fibre in fresh myelin — remyelination, the repair MS disrupts

What our MS patients report.

A registry of what people with MS have reported since 2019, measured at follow-up and shown as it is. Across the 124 people with MS we have supported, improvement or stabilisation in at least one area is common — but outcomes vary from person to person, and an average is never a promise.

Share of MS patients reporting a meaningful improvement or stabilisation · 124 patients, since 2019

Walking, balance and mobility81%
Muscle strength and coordination80%
Cognition and concentration78%
Sensation and bladder control77%
Fatigue and daily energy83%
Overall quality of life84%

3.5 years

Average follow-up with sustained neurological stability across our MS patients.

Every result is individual — it depends on your MS subtype, baseline disability and your body's own biology.

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How we treat MS.

No two protocols are the same. A medical board builds your plan from up to five biological components — combined, sequenced and dosed for your subtype and stage. Each works on a different driver of MS, and together they aim to calm the immune attack, support myelin repair and improve how you function day to day.

Non-surgical — delivered by infusion or targeted injection, safe across all disability levels
Works alongside your existing disease-modifying therapy
No rejection risk and no immunosuppression
Targets both the immune attack and the neurodegeneration, not only symptoms

In MS the immune system attacks the myelin that insulates your nerves. T-regulatory cells are the immune system's own off-switch for this self-attack — they calm the autoreactive cells and rebuild tolerance within the nervous system, reducing both relapses and background inflammation, without the blanket immunosuppression that would leave you exposed. Prepared from your own blood, or from a certified donor. This is the component we lead with in MS.
Multipotent cells that calm the autoimmune inflammation around your nerves and support the conditions for myelin repair, protecting the fibres that remain. They carry almost no rejection markers, so they can be used without immunosuppression, whether drawn from your own bone marrow or a matched donor.
Nanoscale vesicles that carry repair signals across the blood–brain barrier to the sites of active demyelination — reaching the oligodendrocytes that make new myelin, in regions whole cells struggle to reach.
Non-invasive electrical stimulation of the compromised circuits. In MS many pathways are partially demyelinated rather than destroyed; low-intensity currents help signals cross them again — supporting walking stability, coordination and reduced spasticity. No implant, no surgery and no anaesthesia.
Bioactive peptides, chosen for your metabolic profile, that support mitochondrial function in tired neurons — easing the fatigue MS brings and keeping your cells supplied with the energy the rest of the treatment depends on.

Discuss your case

What to expect, step by step.

It begins with a conversation, and no obligation. Here is how treatment takes shape.

Free medical review

A physician reviews your diagnosis, MS subtype, history and goals remotely. No cost, no obligation.

Eligibility & plan

The medical board studies your documents and tells you honestly whether we can help — then designs your protocol.

Laboratory preparation

Your cells are collected, prepared and quality-tested in our own laboratory, with full traceability. About 2–3 weeks.

Treatment in Budapest

Delivered by infusion or targeted administration under medical supervision. We arrange your flights, transfers and accommodation.

Supervised rehabilitation

A specialist rehabilitation plan adapted to your gait, balance and functional status, at the centre or remotely.

Long-term follow-up

A medical wristband, a dedicated coordinator and ongoing access for reassessment as things change.

Safety, and an honest word on expectations.

The treatment is well-tolerated across all MS subtypes and disability levels. Mild, short-lived reactions can happen — brief fatigue, injection-site sensitivity, a low-grade temperature — and usually pass within a day or two. Before every session there is a final on-site assessment; if your neurological status has changed, we adjust or postpone. We will only take your case when we believe we can realistically help.

Assessed individually before we proceed

Active infection or fever
Active cancer, or ongoing chemo- or radiotherapy
Severe heart or kidney failure
Pregnancy

These are standard contraindications. One alone does not automatically rule you out — each is weighed against your full clinical picture.

A patient receiving regenerative therapy in a calm treatment room, a clinician attending

The work continues after Budapest.

In a long-term condition like MS, the months after treatment matter as much as the treatment. A medical wristband streams your data to our team, a rehabilitation specialist and a personal consultant stay in regular contact, and your protocol is adjusted as your needs change.

A patient and a member of the medical team in conversation at the institute

From our MS patients and their families.

They told me secondary progressive MS does not respond to treatment, and I had accepted that. A year on, my balance improved enough that I stopped using the walker indoors and I cook for myself again. My physiotherapist in Turin measured my gait speed going up for the first time in four years.

Patient · Secondary progressive MS · Italy

Fourteen months without a relapse. Before, they came every three or four months. The heaviness in my legs lifted and I am back to walking the dog in the morning. My neurologist confirmed the inflammatory activity has calmed considerably.

Patient · Relapsing-remitting MS · Kazakhstan

The fatigue was the worst part — completely drained by noon, impossible to work or parent properly. That changed gradually. I get through the full day now, my concentration came back, and I finished a work project I had abandoned months earlier.

Patient · RRMS · United Kingdom

My wife needed help getting dressed. After the programme she started managing on her own again. The numbness in her hands faded and her grip came back. She says her legs feel like they belong to her again.

Husband of a patient · Multiple sclerosis · Netherlands

We did the programme with Mum even though she could not travel far. Her speech became clearer, she started remembering our phone conversations, and the tremor in her right hand reduced. Last month she called to say she had been to the market alone.

Daughter of a patient · Progressive MS · France

I was honest with myself that MS does not simply go away. But two years on the relapses have stayed away, my vision is steadier and I have gone back to teaching part-time. They were straight with me about what was realistic.

Patient · Relapsing-remitting MS · Italy

Every case is different. Request a review to talk through yours with our medical team.

Request a medical review for MS.

Send us your diagnosis and we will review it. A medical advisor will be in touch — and will stay with you through the whole treatment as your direct line to the medical team. Free, and no obligation.

By submitting this form, you consent to Caplan processing your personal data for the purpose of medical consultation in accordance with applicable data protection regulations.

The evidence we build on.

Our approach draws on published, peer-reviewed research into cell and regenerative therapy for multiple sclerosis. A selection of the studies that inform it:

These studies inform our protocol. They report findings from research populations, and every patient's response is different. We assess what they mean for your case individually.

Mesenchymal stem cells vs placebo in MS (MESEMS) — Phase 2 randomised trialPubMed 34687636
Mesenchymal stem cell therapy in multiple sclerosis — systematic review and meta-analysisPubMed 37834955
Neural stem cell transplantation in progressive MS — Phase 1 studyPubMed 36624312
Allogeneic MSC-derived exosome therapy for progressive MSClinicalTrials NCT07146087
Cellular and exosome-based therapies in neuroinflammatory syndromesClinicalTrials NCT07145502